I'm not really too sure about protocols. As I mentioned, I've never use it or had an athlete use. As far as what it can do, B12 is most commonly used for combating fatigue. This is usually in the case of people with B12 deficiency but some research points to it perhaps being an effective way of increasing energy in those not B12 deficient. It is also important for normal nerve cell activity, DNA replication, and can also decrease the risk of heart disease, stroke, and potentially other diseases like Alheimers and Osteoporosis. Another thing you might be interested in knowing is that I believe I remember someone telling me you could take B12 in the form of a nasal gel that was more effective than the shots (I might be mixing things up here, I'm not really sure). Like I said though I don't have much experience with it and couldn't attest to that (if in fact I am recalling correctly).