I noted insulin control by specifying what you consume with respect to sugar before physical activity should differ from what you consume after such activity.
The typical american diet is full of overindulgence and gluttony. The typical Mediterranean and Pacific Rim diets are less calorie dense than american ones. In a country were "Burritos as Big as your Head" and Super Sizing is the norm, what do you expect a nation of ectomorphs?
To enter the bloodstream, yes, it's the same. In the bloodstream, cholesterol metabolism plays a big role in the distribution, transport, and storage of lipids. The interplay between cholesterol metabolism and the different fatty-acid chains is more complicated and there is some genetic, some differences between the different chains of fatty-acids, etc…
I don't believe in a thread that starts with supplementation that I could possibly be neglecting micronutrients when taking a centrum is all you need to supplement that.